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4.4: Genome Analysis by Large Scale Sequencing - Biology

Whole genomes can be sequenced both by random shot-gun sequencing and by a directed approach using mapped clones.A seminal advance from J. Craig Venter and his colleagues at The Institute for Genome Research in 1995 heralded a new era in genome analysis. They reported the complete sequence of the genome of the bacterium Haemophilus influenza, all 1,830,137 bp (Fleischmann et al.
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